Brit Jonathan Ive, Apple's vice president of industrial design, has been nominated for the first Designer of the Year award, presented by London's Design Museum.
He competes against the makers of Grand Theft Auto: Vice City, jewelery designer Solange Azagury-Partridge, and Dutch product designer Tord Boontje.
Jurors include fashion designer Paul Smith, who said: "The four nominees have all made fantastic contributions to the world of design. Their work in 2002 was exceptional."
The New York Times has called Ive "perhaps the most influential designer in the computer world."
The winner of the £25,000 prize will be announced in June.